Largest nonprofits in Mississippi by revenue
| # | Nonprofit | City | Focus area | Revenue |
|---|---|---|---|---|
| 1 | North Mississippi Medical Center Inc | Tupelo | Health Care | $1.1 billion |
| 2 | St Dominic-Jackson Memorial Hospital | Jackson | Health Care | $618.6 million |
| 3 | Mississippi Baptist Medical Center | Jackson | Health Care | $616.5 million |
| 4 | Baptist Memorial Hospital-Desoto Inc | Southaven | Health Care | $392.5 million |
| 5 | Baptist Memorial Hospital-North Mississippi Inc | Oxford | Health Care | $311.1 million |
| 6 | Baptist Memorial Hospital-Golden Triangle Inc | Columbus | Health Care | $307.7 million |
| 7 | Anderson Regional Medical Center | Meridian | Health Care | $279.8 million |
| 8 | Baptist Memorial Hospital Union County Inc | New Albany | Health Care | $242.8 million |
| 9 | Rush Medical Foundation | Meridian | Health Care | $192.6 million |
| 10 | Mississippi State University Foundation Inc | Ms State | Human Services | $144.8 million |
| 11 | Mississippi College | Clinton | Education | $140.4 million |
| 12 | William Carey University | Hattiesburg | Not listed | $125.1 million |
| 13 | Singing River Gulfport | Gautier | Not listed | $124.4 million |
| 14 | Kings Daughters Medical Center | Brookhaven | Health Care | $121.8 million |
| 15 | University Of Mississippi Foundation | Oxford | Education | $115.8 million |
| 16 | Mississippi State University Educational Building Corporation | Ms State | Health Care | $94.9 million |
| 17 | Bulldog Club | Ms State | Not listed | $94.1 million |
| 18 | Mississippi Methodist Hospital Rehabilitation Center Inc | Jackson | Health Care | $88.3 million |
| 19 | Medical Foundation Of Central Mississippi Inc | Jackson | Health Care | $81.9 million |
| 20 | North Mississippi Primary Health Care Inc | Ashland | Health Care | $80.4 million |
| 21 | Mississippi Action For Progress Inc | Jackson | Education | $73.1 million |
| 22 | Clay County Medical Corporation | Tupelo | Health Care | $70.9 million |
| 23 | Monroe Health Services Inc | Tupelo | Health Care | $66.5 million |
| 24 | Ole Miss Athletics Foundation | Oxford | Education | $60.2 million |
| 25 | Belhaven University | Jackson | Education | $59.1 million |
The full list includes all 543 Mississippi nonprofits with $1M+ revenue, with street address, ZIP, EIN, assets, income and tax period, plus every other state.
Mississippi cities with the most $1M+ nonprofits
- Jackson: 126
- Tupelo: 48
- Hattiesburg: 26
- Gulfport: 23
- Meridian: 22
- Ridgeland: 17
- Biloxi: 10
- Oxford: 9
- Greenville: 9
- Mccomb: 8
Most common focus areas
- Education: 112
- Health Care: 86
- Human Services: 73
- Arts, Culture & Humanities: 26
- Housing & Shelter: 24
- Community Improvement & Capacity Building: 23
- Philanthropy, Voluntarism & Grantmaking Foundations: 19
- Religion-Related: 16
Where does this data come from?
The IRS Exempt Organizations Business Master File, downloaded in October 2026. Figures are as reported on each organization's latest return on file with the IRS. Personal contact names are not included.